Press mailing and mandatory publicity with the new NAVIGATORPlease enter your e-mail adress.You will then be sent a link to reset your password.Hamburg (pts018/08/13/2021/09:40) - Advancing age is accompanied by changes in the intestinal microbiota.These are characterized by a loss of beneficial commensal microbes, which are affected in frequency and activity by intrinsic and extrinsic factors such as diet, medications, a sedentary lifestyle in old age, and chronic diseases.Typical changes are a loss of diversity, which is associated with gut-associated comorbidities.The age-related microbiome changes disrupt the gut balance and create a pro-inflammatory environment that produces typical signs of aging.In particular, the ongoing inflammatory reactions produce reactive oxygen radicals that inactivate strictly anaerobic but very beneficial bacteria and favor the oxygen-tolerant unfavorable bacteria, which is often observed in the elderly.The German research team of PhytoEffect, around founder Dr.-Ing.Henning Rosenfeld has developed a new prebiotic dietary supplement that supports the human microbiome purely from plants and thus combats many complaints where they arise - in our intestines.https://www.phytoeffekt.com/produkt/jo2-phytoOur gut makes us oldThe connections between aging and emerging microbial dysbioses with the typical consequences of intestinal leakage, inflammation and decline in immune function can serve as a therapeutic approach to reverse the immune aging clock and potentially support overall good health in old age.Comparative studies of healthy-aged Chinese and Italians, despite differences in genetics, diet, and environmental conditions, have revealed striking similarities in certain types of bacteria that may be responsible for healthy aging (although, again, it's too early to speak of causality).These include the SCFA-producing bacteria such as Akkermansia spp.and Clostridia XIVa.SCFA are short-chain fatty acids that come from bacterial metabolism and have a variety of positive effects in the body.These bacteria are increasingly stimulated to grow by naringenin (from citrus fruits, tomatoes).Unfortunately, the naringenin is quickly excreted from the body, so that too little reaches the microbiome in the large intestine.With JO2-Phyto from Phytoeffekt https://www.phytoeffekt.com you can keep the intestinal flora healthy with the power of natural, prebiotic plant substances, which are transported directly into the large intestine through the specially developed capsule and are not excreted beforehand via the liver and kidneys .Overall, frailty is associated with decreasing bacterial diversity in the gut.Studies on 100-year-olds who have been shown to have successfully aged in good health have found that diversity can even increase with age, or that diversity can decrease with the growth of health-promoting, less dominant species (such as Akkermansia, Bifidobacterium , Christensenellaceae).What is your bowel age?The microbiome is a dynamic structure that is subject to permanent, profound changes for the individual phases of life.But sometimes maladaptations occur that trigger immune deficiencies or inflammation and in turn have a negative impact on the intestinal community.An inflammatory vicious cycle is a major contributor to aging and frailty.The microbiome should remain relatively stable between 30 and 70 years.The provision for a diverse microbiome in old age should not start at the age of 70, but in the middle age between 40 and 50.Microbiome-active plant substances are particularly suitable for this because they have a high anti-inflammatory effect and allow many of the right bacteria to grow.In addition, microbiome-active naringenin acts against osteoporosis.A sign of aging in which more and more bone tissue is broken down (bone loss).In traditional Chinese medicine, the naringenin in the Rhizoma drynariae (Gusuibu) is used to treat osteoporosis.Research director Dr.Henning Rosenfeld: "The microbiome is subject to dynamic change over the lifespan. Whether we are fit or frail in old age can actually be down to the intestinal bacteria!"https://www.phytoeffekt.com/produkt/jo2-phyto